Baltimore Orioles at Philadelphia Phillies 9/22/21 - MLB Picks & Predictions

On Wednesday, the Baltimore Orioles conclude a three-game interleague series on the road against the Philadelphia Phillies. Baltimore improved to 48-102 following a 2-0 victory over the Phillies in the opening game of the series on Monday. The victory snapped a three-game losing streak for Baltimore but the Orioles have lost eight of the last 10 and are last in the American League East 44 ½ games behind first place Tampa Bay.

Cedric Mullins is batting .301 to lead Baltimore and the center fielder leads the Orioles in hits with 169 and on-base percentage at .368. Third baseman Ryan Mountcastle is the leader in home runs with 30 and RBIs with 83. On Wednesday, Baltimore will send Keegan Akin to the mound. The left-hander is 2-10 with an ERA of 6.93, 76 Ks and 39 BBs.

Philadelphia dropped to 76-74 following its two-run loss on Monday to Baltimore. The Phillies have lost two straight and have fallen to three games behind first place Atlanta in the National League East and are 4 ½ games behind the second and final spot in the NL wildcard chase.

Right fielder Bryce Harper is batting .311 to lead Philadelphia and has 33 home runs, 80 RBIs and an on base percentage of .427 to lead the Phillies in each category. Shortstop Jean Segura is the leader in hits with 143. On Wednesday, Philadelphia will send Zack Wheeler to the mound. The right-hander is 14-9 with an ERA of 2.83, 231 Ks and 43 BBs.