Baltimore Orioles at Boston Red Sox 9/26/22 - MLB Picks & Predictions

Last Updated: 09/25/2022 at 11:15 PM ET

Baltimore Orioles at Boston Red Sox 9/26/22 - MLB Picks & Predictions

Historic Fenway Park will play host to a Monday night MLB battle between the Baltimore Orioles and the Boston Red Sox. The Orioles (79-73) are four games below .500 on the road and trail Seattle by four full games in the race for the final AL Wild Card spot. On Sunday, Baltimore batters struck out 15 times during a 6-3 home loss versus Houston in 11 innings. 

Thirty-one year old righty Jordan Lyles (11-11 4.50 ERA) will head to the hill for the Orioles in this contest. Last time out, Lyles threw a complete game three hitter and struck out six batters during an 8-1 home victory versus Detroit.

The Boston Red Sox are in the midst of a five-game losing streak and are trapped in the AL East Division basement. Last night, Boston managed just one hit during a 1-0 rain shortened road loss against New York that was called after six innings. SP Brayan Bello (2-7) gave up two runs (1 ER) and took the loss for the Red Sox, who fell to 72-80 on the year.

Rookie right-hander Connor Seabold (0-3 10.47 ERA) will make his fifth career major league start for the Red Sox. Through 16 plus innings, Seabold has been knocked around for 30 hits and 19 earned runs.

Boston 2B Trevor Story has been placed on the 10-day injured list with a left heel contusion. Through 152 games, Baltimore ranks 20th in OPS and 20th in runs scored. For the season, Boston ranks 9th in OPS and 10th in runs scored. Take the Orioles to win on the road. Final Score Prediction, Baltimore Orioles win 6-4.

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