USC at Arizona 10/29/22 - College Football Picks & Predictions

Last Updated: 10/28/2022 at 12:48 PM ET

USC at Arizona 10/29/22 - College Football Picks & Predictions

The No. 12 ranked USC Trojans visit Arizona Stadium in Tucson, Arizona on Saturday to play the Arizona Wildcats. USC dropped to 6-1 overall and 4-1 in Pac-12 play following its 4-1 loss to the Utah Utes a week ago this past Saturday. USC had a bye in Week 8. USC gave up 562 yards of total offense to Utah while gaining 556 yards of total offense. However, USC squandered a 21-7 second-quarter lead and gave up the winning touchdown to Utah with 48 seconds to play.

USC quarterback Caleb Williams has passed for 1,971 yards with 19 touchdowns and just one interception. Travis Dye is the leading rusher with 647 yards and seven touchdowns, while Jordan Addison is the leading receiver with 585 yards and seven touchdown receptions. On defense, linebacker Eric Gentry is the leading tackler with 52. USC has 24 quarterback sacks and 12 interceptions.

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Arizona is 3-4 overall and 1-3 in Pac-12 play following its 49-39 loss to the Washington Huskies a week ago this past Saturday and the Wildcats had a bye during Week 8. Arizona's defense gave up 595 yards of total offense to Washington while the Wildcats offense gained 526 yards of total offense. Jayden de Laura passed for 400 yards and four touchdowns, but it was not enough as the Wildcats gave up seven touchdowns to the Huskies.

Arizona quarterback Jayden de Laura has passed for 2,274 yards with 19 touchdowns and seven interceptions. The leading rusher is Michael Wiley with 297 yards and three touchdowns, while the leading receiver is Jacob Cowing with 737 yards and seven touchdown receptions. On defense, linebacker Jerry Roberts is the leading tackler with 49. Arizona has nine quarterback sacks and two interceptions.

USC will easily defeat Arizona on the road Saturday but the play here is under. The OVER has cashed in four of Arizona's last five as well as in five of the last seven games that Arizona has played against an opponent from the Pac-12. In addition, the OVER has cashed in five of USC's last six versus an opponent from the South Division of the Pac-12. USC is scoring an average 40.4 points per game and faces an Arizona defense that is allowing an average of 36.3 points per game. Final Score Prediction, USC Trojans win and cover ATS 49-21.

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