Ohio State vs Northwestern Picks and Prediction – 11/16/2024

By: Eddie Kline |

Last Updated: 11/11/2024 at 12:13 AM ET

Ohio State at Northwestern 11/16/24 - College Football Picks & Predictions
Game Start: 11/16/2024, 5:00 PM UTC
Latest Odds: OSU -30.5 ; Total 45.5

Ohio State vs Northwestern Prediction

Historic Wrigley Field will play host to a Saturday afternoon college football clash between the Ohio State Buckeyes and the Northwestern Wildcats. Make sure you are ready for all the football action with our college football picks. The second-ranked Buckeyes (8-1) lead the Big Ten Conference in total defense and are allowing just 12 points per game. On Saturday, Ohio State limited Purdue to 206 yards of total offense during a 45-0 home victory. 

Ohio State QB Will Howard completed 21 of 26 passes for 260 yards and three touchdowns. Treveyon Henderson needed just six carries to rush for a game-high 85 yards and a score. Jeremiah Smith contributed 87 receiving yards and a touchdown for the Buckeyes. 

The Northwestern Wildcats have dropped four of their first six Big Ten conference games and need wins in two of their final three games to become bowl eligible. The Wildcats (4-5) rank last in the conference in total offense and are averaging a shade below 20 points per contest. Last time out, RB Joseph Himon II caught a 22-yard touchdown in overtime to lift Northwestern to a 26-20 road victory against Purdue.

Himon II added a game-high 78 rushing yards and a long touchdown run that gave Northwestern a 10-3 lead after one quarter. WR Cam Porter scored a one-yard touchdown run and caught eight passes for 85 yards. Northwestern racked up 424 yards of total offense and possessed the ball for 35 minutes. 

Ohio State vs Northwestern Pick Analysis

Ohio State is riding a ten-game winning streak against Northwestern and won the most recent meeting by a 21-7 score. The Buckeyes have a huge showdown against undefeated Indiana next week and likely will keep things rather vanilla on offense. Take the Wildcats to play inspired and get the cover. Final Score Prediction, Ohio State Buckeyes win 31-14.

Our Free NCAA Football Pick for Northwestern vs Ohio State

Northwestern Wildcats +30.5

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