Louisville at Notre Dame 10/17/20 - College Football Picks & Predictions

Last Updated: 10/15/2020 at 6:22 PM ET

The Louisville Cardinals visit Notre Dame Stadium in South Bend, Indiana on Saturday for an Atlantic Coast Conference showdown with the Notre Dame Fighting Irish. Louisville fell to 1-3 following its 46-27 loss to Georgia Tech on Friday. The Cardinals led by two-touchdowns at one point but were outscored 20-0 in the fourth quarter. Louisville running backs coughed up the ball three times on a rainy night in Georgia.

Malik Cunningham has thrown for 986 yards, with nine touchdowns, five interceptions and has been sacked 14 times. Javian Hawkins is the leading rusher for Louisville with 46 yards and three touchdowns, while Tutu Atwell is the leading receiver with 281 yards and four touchdowns and Dez Fitzpatrick has 234 yards receiving and one touchdown reception. On defense, linebacker Dorian Etheridge has a team-high 27 tackles.

Notre Dame kept its perfect record intact with a 42-26 victory over the Florida State Seminoles on Saturday and improved to 3-0 in the process. Quarterback Ian Book passed for 201 yards and two touchdowns in the victory while Javon McKinley caught five passes for 107 yards. However, the top producer on offense was running back Kyren Williams who rushed for 185 yards and two touchdowns. Notre Dame gained 554 yards of total offense but allowed 405 yards to the Seminoles.

Ian Book has passed for 608 yards with three touchdowns, one interception and has been sacked three times. Running back Kyren Williams has rushed for 359 yards and four touchdowns, while wide receivers Tommy Tremble and Javon McKinley each have 114 yards. On defense, Jeremiah Owusu-Koramoah is the leading tackler for Notre Dame with 15.

Although Notre Dame will easily defeat Louisville in this matchup on Saturday, the play here is the UNDER. The UNDER has cashed in seven of Notre Dame's last 11 when the Fighting Irish are the favorites and in five of Notre Dame's last six played at home on Saturday. The Cardinals will have a difficult time scoring against the Notre Dame defense. Final Score Prediction, Notre Dame Fighting Irish win but our best play is UNDER 27-14.

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