Penn State vs Indiana Picks and Prediction – 2/27/2025

By: Thomas Pemberton |

Last Updated: 02/25/2025 at 10:25 PM ET

Penn State at Indiana 02/26/25 - NCAAB Picks & Predictions
Game Start: 2/27/2025, 1:30 AM UTC
Latest Odds: IND -5.5 ; O/U 151.5

Penn State vs Indiana Prediction

The Indiana Hoosiers will host the Penn State Nittany Lions on Wednesday. Indiana is 16-11 on the season. The Hoosiers have won just three of their last ten games. Indiana is 12-4 on their home court. The Hoosiers are averaging 75,5 points scored per game. Stay up to date with our expert's college basketball picks. 

The Indiana Hoosiers beat Purdue in their last game played 73-58. Malik Reneau and Trey Galloway each scored 15 points. Oumar Ballo added 12 points and grabbed 5 rebounds. Ballo leads Indiana on the season with an average of 13.4 points scored per game. 

The Penn State Nittany Lions are 15-13 on the season. Penn State is 3-7 over their last ten games. The Nittany Lions have won two straight games and they carry a 2-7 road record. Penn State lost to Indiana back in January by six points. 

The Penn State Nittany Lions beat Minnesota in their last game 69-60. Yanic Konan Niederhauser led the way with 24 points. Ace Baldwin and Freddie Dilione each added 10 points. Baldwin leads Penn State on the season with an average of 13.7 points scored per game. 

Penn State vs Indiana Pick Analysis

The Indiana Hoosiers head into Wednesday as home favorites. Indiana is hoping to beat Penn State for a second time this year. Penn State is seeking a third straight win but they have been bad on the road this season. Back the Hoosiers at home. Final Score Prediction, Indiana Hoosiers win and cover ATS 75-68. 

Our Free NCAA Basketball Pick for Indiana vs Penn State

Indiana Hoosiers -5.5