Loyola-Chicago vs San Francisco Picks and Prediction – 3/23/2025

By: David Anicetti |

Last Updated: 03/22/2025 at 8:19 PM ET

Loyola-Chicago at San Francisco 03/23/25 - NCAAB Picks & Predictions
Game Start: 3/23/2025, 11:00 PM UTC
Latest Odds: SF -6.5 ; O/U 144.5

Loyola-Chicago vs San Francisco Prediction

The Loyola Chicago Ramblers visit The Sobrato Center in San Francisco on Sunday to play the San Francisco Dons in the second round of the NIT. Loyola reached the second round after defeating San Jose State 73-70 on Wednesday night. Des Watson was the leading scorer for Loyola Chicago with 24 points. The Ramblers shot 49.1% overall and held San Jose State to 36.8%. Keep updated on College Basketball with our expert college basketball picks.

Des Watson leads Loyola Chicago in the scoring, averaging 13.2 points per game and Jayden Dawson is second, averaging 13.0 points per game. Miles Rubin is the leading rebounder, averaging 5.4 per game and Kymany Houinsou is the leader in assists, averaging 3.3 per game. Loyola Chicago scores an average of 73.5 points per game, shooting 45.8% overall and 35.4% from 3-point territory.

The San Francisco Dons beat the Utah Valley Wolverines 79-70 in their first-round NIT matchup Wednesday. Malik Thomas was the leading scorer for San Francisco with 21 points but shot just 6-for-19. San Francisco shot 44.6% overall and 36.4% from 3-point territory while holding Utah Valley to 41.4% shooting overall and 19.0% from 3-point territory. The Dons committed 12 turnovers to 13 for Utah Valley.

Malik Thomas leads San Francisco in scoring, averaging 19.4 points per game. Marcus Williams is second in scoring and the leader in assists, averaging 15.1 points and 4.3 assists per game. Tyrone Riley IV is the leading rebounder, averaging 6.0 rebounds per game. San Francisco scores an average of 75.9 points per game, shooting 45.7% overall at 33.8% from 3-point territory.

Loyola-Chicago vs San Francisco Pick Analysis

The San Francisco Dons will win this second-round NIT matchup and move on to the third round but the play here is OVER. The OVER has cashed in four of the last five games Loyola Chicago has played on the road, each of San Francisco's last five games overall, four of San Francisco's last five games versus Atlantic 10, and each of San Francisco's last six played in March. Final Score Prediction, San Francisco Dons win but our best play is OVER 77-73.

Our Free NCAA Basketball Pick for San Francisco vs Loyola-Chicago

Over 144.5