Iowa vs USC Picks and Prediction – 1/15/2025

By: Ricky MacKenzie |

Last Updated: 01/14/2025 at 12:10 AM ET

Iowa at USC 01/14/25 - NCAAB Picks & Predictions
Game Start: 1/15/2025, 3:30 AM UTC
Latest Odds: USC -2.5 ; O/U 162

Iowa vs USC Prediction

This Tuesday, Payton Sandfort and the Iowa Hawkeyes will take on Desmond Claude and the USC Trojans in a non-conference showdown. Get our free NCAAB Picks all season long! The Hawkeyes enter the matchup with a 12-4 record, riding high after an 85-60 victory over Indiana on Saturday. Sandfort has been a key player for Iowa, providing scoring and versatility to fuel their fast-paced offense.

Iowa has been effective in creating scoring opportunities through their strong ball movement and ability to shoot from beyond the arc. To secure a victory against USC, Sandfort and the Hawkeyes will need to maintain their offensive efficiency while focusing on limiting defensive lapses.

The Trojans, holding a 10-6 record, are coming off a solid 82-72 win over Illinois on Saturday. Claude has been a standout for USC, leading with his scoring ability and strong defensive play. The Trojans have shown resilience this season and will look to continue building momentum on both ends of the court.

For USC, controlling Iowa’s perimeter shooting and matching their offensive tempo will be critical. Claude will need to deliver a strong performance while the supporting cast steps up to challenge Iowa’s defense.

Iowa vs USC Pick Analysis

This game features Sandfort’s scoring and leadership for Iowa against Claude’s two-way impact for USC. While the Trojans bring energy and determination, the Hawkeyes’ recent form and offensive firepower give them the edge. Take the Hawkeyes to win this one and to cover the spread here on the road. Final Score Prediction, Iowa Hawkeyes win 78-70.

Our Free NCAA Basketball Pick for USC vs Iowa

Iowa Hawkeyes +2.5