Houston vs Duke Picks and Prediction – 4/5/2025

The Houston Cougars will be in San Antonio Saturday night for a Final Four matchup against the Duke Blue Devils. Houston has 34 wins and four losses this season riding a long winning streak after a 19 point victory against Tennessee in the elite eight. Offensively the Cougars averaged 74.2 points on 45.5% shooting from the floor this season. Defensively Houston is one of the best teams in the country and have allowed an average of 56.5 points per game through their first four NCAA tournament games. Stay up to date with our College Basketball Picks.

Defensively Houston was stifling last Sunday in the elite 8 giving up just 50 points on 28.8% shooting on 17.2% from beyond the arc. The Cougars won the rebounding battle by 7 and forced 9 turnovers in the game period offensively Houston did just enough scoring 69 points on 42.4% shooting knocked down 9 triples. LJ Cryer led the way for the Houston offense with 17 points on 17 shots.

The Duke Blue Devils come into the final four is the best team in the nation with 30 five wins and three losses on the year as they ride a winning streak dating back before Thanksgiving. Offensively Duke is one of the best teams in the country averaging 83.7 points on 49.6% shooter from the floor of this season and have averaged 91.75 points per game during the NCAA tournament.

Defensively Duke shut Alabama down in the Elite 8 giving up 65 points on 35.4% from the floor. The Blue Devils won the rebounding battle by double digits and forced 11 turnovers in the wind. Offensively Duke rolled scoring 85 points including 46 in the first half on 53.6% shooting in the Blue Devils knocked down 6 triples in the game. Kon Knueppel carried the load for the Duke offense with 21 points on 15 shots.

This is a matchup between 2 of the best teams in the nation and it will live up to the hype. Duke is the most complete team in the country and Houston has the best defense. Look for Duke to rely on their future NBA players to do enough down the stretch of this game to get it done. Take Duke Saturday in the Final 4 to punch their ticket into the chip with a win and cover. Final Score Prediction, Duke Blue Devils win and cover 75-66.