Redblacks vs Stampeders Picks and Prediction – 6/21/2025

By: David Anicetti |

Last Updated: 06/15/2025 at 8:08 PM ET

Ottawa Redblacks at Calgary Stampeders 06/21/25 - CFL Picks & Predictions
Game Start: 6/21/2025, 8:00 PM UTC
Latest Odds: OTT -1.5 ; O/U 50.5

Redblacks vs Stampeders Prediction

The Ottawa Redblacks look for their first win of the season on Saturday when visiting the Calgary Stampeders. Ottawa dropped to 0-2 following its 39-18 loss to the Montreal Alouettes on Friday night. Ottawa quarterback Matthew Shiltz passed for 205 yards with one touchdown and three interceptions. The Ottawa defense gave up 438 yards of total offense to Montreal. Keep up to date with all the CFL action with our CFL picks

Ottawa quarterback Dru Brown has thrown for 413 yards with two touchdowns. The leading rusher is William Stanback with 55 yards and one touchdown, and the leading receiver is Bralon Addison with 164 yards and one touchdown reception. Adarius Pickett is the leading tackler with 11. Ottawa’s offense is scoring an average of 22.0 points per game, while allowing an average of 35.0 points per game.

The Calgary Stampeders look for their third straight win to open the season on Saturday when hosting Ottawa. Calgary improved to 2-0 following its 29-19 victory on Saturday over the Toronto Argonauts. Calgary quarterback Vernon Adams Jr passed for 301 yards and rushed for 54 yards. Adams scored one rushing touchdown. The leading receiver was Jalen Philpot with 117 yards.

Quarterback Vernon Adams Jr has thrown for 585 yards with two interceptions. The leading rusher is Dedrick Mills with 122 yards and four touchdowns, while the leading receiver is Jalen Philpot with 138 yards. The Stampeders have not thrown any touchdown passes. Calgary is scoring an average of 33.5 points per game, while allowing an average of 22.5 points per game. 

Redblacks vs Stampeders Pick Analysis

The Calgary Stampeders are off to a strong start with two consecutive victories, scoring an average of 33.5 points per game, which is second in the CFL, while allowing an average of just 22.5 points per game, which is third. The Stampeders have covered the number in each of the first two, while Ottawa has failed to cover the nut in each of its first two. The Redblacks are last in points allowed at 35.0 points per game. Final Score Prediction, Calgary Stampeders win and cover ATS 24-22.

Our Free CFL Pick for Calgary Stampeders vs Ottawa Redblacks

Calgary Stampeders +1.5